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Infections and their complications are a very important clinical area in the intensive care unit setting. Community-acquired infections and nosocomial infections both contribute to the high level of disease acquisition common among critically ill patients. The accurate diagnosis of nosocomial infections and the provision of appropriate therapies, including antimicrobial therapy effective against the identified agents of infection, have been shown to be important determinants of patient outcome. Critical care practitioners are in a unique position in dealing with infectious diseases. They are often the initial providers of care to seriously ill patients with infections. Additionally, they have a responsibility to ensure that nosocomial infections are prevented and that antimicrobial resistance is minimized by prudently employing antibiotic agents. It is the editors' hope that this book will provide clinicians practicing in the intensive care unit with a reference to help guide their care of infected patients. To that end they have brought together a group of international authors to address important topics related to infectious diseases for the critical care practitioner.

Medicine & Public Health. --- Intensive / Critical Care Medicine. --- Infectious Diseases. --- Emergency Medicine. --- Pneumology/Respiratory System. --- Medical Microbiology. --- Medicine. --- Microbiology. --- Emergency medicine. --- Critical care medicine. --- Emerging infectious diseases. --- Pneumology. --- Médecine --- Microbiologie --- Médecine d'urgence --- Soins intensifs --- Maladies infectieuses émergentes --- Intensive care units. --- Nosocomial infections. --- Critical care medicine --- Communicable diseases --- Intensive care units --- Infection --- Patient Care --- Therapeutic Uses --- Communicable Disease Control --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Hospital Units --- Anti-Infective Agents --- Critical Care --- Intensive Care Units --- Cross Infection --- Diagnosis, Differential --- Infection Control --- Diagnosis --- Communicable Diseases --- Community-Acquired Infections --- Pharmacologic Actions --- Public Health Practice --- Bacterial Infections and Mycoses --- Health Facilities --- Health Services --- Therapeutics --- Diseases --- Chemical Actions and Uses --- Public Health --- Health Care Facilities, Manpower, and Services --- Chemicals and Drugs --- Health Care --- Environment and Public Health --- Medicine --- Infectious Diseases --- Emergency Medicine --- Health & Biological Sciences --- Communicable diseases. --- Critical care units --- ICUs (Health facilities) --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Intensive care --- Intensive medicine --- Hospital wards --- Epidemics --- Emergency medicine

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Migration, Health and Inequality highlights recent developments in the areas of migration, human rights and health from a range of countries. Looking at diverse health issues, from HIV to reproductive and maternal health, and a variety of forms of migration, including asylum-seeking, labour migration and trafficking, it offers a range of linkages between migrant agency, transnationalism and diaspora mechanisms and looks at the impact of migrant health on those communities that are left behind.

Communicable diseases --- Immigrants --- Transmission. --- Health and hygiene. --- Emigrants --- Foreign-born population --- Foreign population --- Foreigners --- Migrants --- Persons --- Aliens --- Communicable disease transmission --- Disease transmission --- Diseases --- Germs, Spread of --- Spread of communicable diseases --- Spread of germs --- Transmission of diseases --- Epidemiology --- Transmission --- Emigration and immigration --- Health. --- Emigration et immigration --- Santé --- Social aspects --- Aspect social --- Human rights --- Politics & government --- Human geography --- Basic rights --- Civil rights (International law) --- Rights, Human --- Rights of man --- Human security --- Transitional justice --- Truth commissions --- Immigration --- International migration --- Migration, International --- Population geography --- Assimilation (Sociology) --- Colonization --- Health aspects --- Health aspects. --- Law and legislation

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Recounting the social, cultural, and scientific history of vaccines, Vaccines: A Biography traces the lineage—the ‘biography’—of individual vaccines, originating with deeply rooted medical problems, following ideas as they are conceived and developed, leading eventually to practical, preventive solutions to major public health problems in society. Yet these are not ‘biographies’ in the traditional sense; they do not trace an individual’s growth and development. These are epic stories of discovery, of risk-takers. They have all the trappings of fiction: strong protagonists who succeed against sometimes great odds, interpersonal conflicts, deceit, political intrigue, ethical dilemmas, and dramatic, if not staged events. They are set in the major centers of Europe and the United States, on farms and in slums, and in exotic venues from Calcutta to French Indochina to Cairo to Panama. They occur in the halls of academia, research laboratories, the chambers of government, and on the battlefields of war. At its core, Vaccine: A Biography is the history of individuals advancing medical science, in the words of the famous physical scientist Isaac Newton, "by standing on the shoulders of giants".

Vaccination --- Vaccines. --- History. --- Infectious Diseases. --- Popular Science in Medicine and Health. --- Medical virology. --- Emerging infectious diseases. --- Virologie médicale --- Maladies infectieuses émergentes --- Communicable diseases -- Prevention -- History. --- Vaccination -- History. --- Complex Mixtures --- Life sciences. --- Immunology. --- Medical microbiology. --- Infectious diseases. --- Medicine --- Microbiology. --- Medicine. --- Health. --- Life Sciences. --- Medical Microbiology. --- History of Medicine. --- Biologicals --- Vaccines --- history. --- Immunobiology --- Life sciences --- Serology --- Microbial biology --- Biology --- Microorganisms --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Health Workforce --- Medicine—History. --- Medicine . --- Personal health --- Wellness --- Physiology --- Diseases --- Holistic medicine --- Hygiene --- Well-being --- Diseases. --- Medical sciences. --- Health Sciences. --- Basic medical sciences --- Basic sciences, Medical --- Biomedical sciences --- Health sciences --- Preclinical sciences --- Sciences, Medical --- Human beings --- Illness --- Illnesses --- Morbidity --- Sickness --- Sicknesses --- Epidemiology --- Health --- Sick

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Although it has long been recognized that what we eat and how we deal with stress play a major role in disease prevention and treatment, it is only recently that the scientific basis of this relationship has been aggressively studied. In Nutrients, Stress, and Medical Disorders, prominent researchers from academia, industry, and medicine survey current clinical findings on the complex interactions between diet, mental health, and stress, and their impact on disease states. The authors consider specific nutrients (fatty acids, glucocorticoids, herbal products, and alcohol), the effects of food, and stress, taking into account even environmental influences other than diet and their effects on stress and central nervous system functions. They give special attention to the influence of stress on physical health, mental health, and cognitive function, including the critical effects of maternal nutritional status and stress levels on fetal physical and mental development, the role of lipids in the development and treatment of depression, the role of fish oil in the development of aggressive behaviors, and the consequences of obesity on stress and the development of eating disorders. Additional chapters examine the effects of stress on chronic disorders, women, and cardiac function, and the influence of inflammation on diet, neurological functions, disease incidence, and cognitive functions. Authoritative and up-to-date, Nutrients, Stress, and Medical Disorders offers health professionals in many areas of research and practice not only an easy-to-understand benchmark review of the importance of nutrition in reducing stress-related chronic diseases and optimizing health, but also insight into exciting possibilities for drug development, the design of therapeutic programs, and future research opportunities.

Stress --- Disease --- Mental Disorders --- Nutritional Physiological Phenomena. --- Stress (Physiology) --- Chronic diseases --- Inflammation --- physiopathology. --- etiology. --- complications. --- Nutritional aspects. --- Stress, Psychological --- Nutritional Physiological Phenomena --- Nutritional aspects --- physiopathology --- etiology --- Nutrition --- physiology. --- Stress (Physiology). --- Mental disorders --- Inflammatory process --- Diseases, Chronic --- NCDs (Noncommunicable diseases) --- Non-communicable diseases --- Non-infectious diseases --- Noncommunicable diseases --- Physiological stress --- Tension (Physiology) --- Medicine. --- Nutrition. --- Public health. --- Medicine & Public Health. --- Public Health. --- Pathology --- Anti-inflammatory agents --- Diseases --- Adaptation (Biology) --- Stress (Physiology) - Nutritional aspects --- Chronic diseases - Nutritional aspects --- Inflammation - Nutritional aspects --- Stress, Psychological - physiopathology --- Disease - etiology --- Mental Disorders - etiology --- Etiology. --- Physiology. --- Complications. --- Physiopathology.

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Clustered survival data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. Frailty models provide a powerful tool to analyse clustered survival data. In contrast to the large number of research publications on frailty models, relatively few statistical software packages contain frailty models. It is demanding for statistical practitioners and graduate students to grasp a good knowledge on frailty models from the existing literature. This book provides an in-depth discussion and explanation of the basics of frailty model methodology for such readers. The discussion includes parametric and semiparametric frailty models and accelerated failure time models. Common techniques to fit frailty models include the EM-algorithm, penalised likelihood techniques, Laplacian integration and Bayesian techniques. More advanced frailty models for hierarchical data are also included. Real-life examples are used to demonstrate how particular frailty models can be fitted and how the results should be interpreted. The programs to fit all the worked-out examples in the book are available from the Springer website with most of the programs developed in the freeware packages R and Winbugs. The book starts with a brief overview of some basic concepts in classical survival analysis, collecting what is needed for the reading on the more complex frailty models. Luc Duchateau is Associate Professor of Statistics at the Faculty of Veterinary Medicine of the Ghent University, Belgium. He is board member of the Quetelet Society (Belgian Region of the International Biometric Society) and of the International Biometric Society Channel Network. He has collaborated extensively with physicians in oncology and allergy, public health workers and veterinarians, and is an author of numerous papers in statistical, medical and veterinarian journals. Paul Janssen is Professor of Statistics at the Centre for Statistics of the Hasselt University, Diepenbeek, Belgium. He is an elected member of the International Statistical Institute. He spent research visits at the Johns Hopkins University (Baltimore, USA) and the University of Washington (Seattle, USA). His research interests include survival analysis, nonparametric estimation, resampling techniques and asymptotic theory.

epidemiologie --- biostatistiek --- Biomathematics. Biometry. Biostatistics --- vormgeving --- besmettelijke ziekten --- Oncology. Neoplasms --- biomathematica --- simulaties --- Artificial intelligence. Robotics. Simulation. Graphics --- oncologie --- Infectious diseases. Communicable diseases --- biometrie --- medische statistiek --- Epidemiology --- Mathematical statistics --- Survival Analysis --- Statistics --- Statistique --- EPUB-LIV-FT LIVSTATI SPRINGER-B --- Statistics. --- 57.087.1 --- 616-036.8 --- Statistical analysis --- Statistical data --- Statistical methods --- Statistical science --- Mathematics --- Econometrics --- 57.087.1 Biometry. Statistical study and treatment of biological data --- Biometry. Statistical study and treatment of biological data --- 616-036.8 Final stage. Termination. Consequences. Results. Successes. Setbacks. Failures. Efficacy. Inefficacy. Survival. Statistics. Mortality in a specific disease --- Final stage. Termination. Consequences. Results. Successes. Setbacks. Failures. Efficacy. Inefficacy. Survival. Statistics. Mortality in a specific disease --- Distribution (Probability theory. --- Oncology. --- Computer simulation. --- Biometry. --- Emerging infectious diseases. --- Probability Theory and Stochastic Processes. --- Statistics for Life Sciences, Medicine, Health Sciences. --- Cancer Research. --- Simulation and Modeling. --- Biometrics. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Tumors --- Distribution functions --- Frequency distribution --- Characteristic functions --- Probabilities --- Biological statistics --- Biology --- Biometrics (Biology) --- Biostatistics --- Biomathematics --- Probabilities. --- Statistics . --- Cancer research. --- Biometrics (Biology). --- Infectious diseases. --- Cancer research --- Probability --- Statistical inference --- Combinations --- Chance --- Least squares --- Risk